Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation

It is known that aging decreases natural resistance to viral diseases due to dysfunctional innate and adaptive immune responses, but the nature of these dysfunctions, particularly in regard to innate immunity, is not well understood. We have previously shown that C57BL/6J (B6) mice lose their natura...

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Bibliographic Details
Published in:Aging Cell
Main Authors: Stotesbury, Colby, Wong, Eric B., Tang, Lingjuan, Montoya, Brian, Knudson, Cory J., Melo‐Silva, Carolina R., Sigal, Luis J.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433008/
https://ncbi.nlm.nih.gov/pubmed/32657004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13170
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