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Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key?

To date the pathophysiology of COVID-19 remains unclear: this represents a factor determining the current lack of effective treatments. In this paper, we hypothesized a complex host response to SARS-CoV-2, with the Contact System (CS) playing a pivotal role in innate immune response. CS is linked wi...

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Pubblicato in:Front Immunol
Autori principali: Meini, Simone, Zanichelli, Andrea, Sbrojavacca, Rodolfo, Iuri, Federico, Roberts, Anna Teresa, Suffritti, Chiara, Tascini, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7432138/
https://ncbi.nlm.nih.gov/pubmed/32849666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02014
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