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Cytoplasmic dynein could be key to understanding neurodegeneration

A new mouse mutation, Sprawling, highlights an essential role for the dynein heavy chain in sensory neuron function, but it lacks the ability of other known heavy-chain mutations to ameliorate neurodegeneration due to defective superoxide dismutase.

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Bibliographic Details
Main Authors: Banks, Gareth T, Fisher, Elizabeth MC
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397497/
https://ncbi.nlm.nih.gov/pubmed/18373888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-3-214
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