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Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner
DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with DNA:RNA hybrids being produced co-transcriptionally by the invasion of the nascent RNA molecule produced in cis with its DNA template. However, it has also been suggested that rec...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7431130/ https://ncbi.nlm.nih.gov/pubmed/32749214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56674 |
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