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Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium
Current strategies to direct therapy-loaded nanoparticles to the brain rely on functionalizing nanoparticles with ligands which bind target proteins associated with the blood–brain barrier (BBB). However, such strategies have significant brain-specificity limitations, as target proteins are not excl...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
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| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7431083/ https://ncbi.nlm.nih.gov/pubmed/32703811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002016117 |
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