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Two distinct amphipathic peptide antibiotics with systemic efficacy

Antimicrobial peptides are important candidates for developing new classes of antibiotics because of their potency against antibiotic-resistant pathogens. Current research focuses on topical applications and it is unclear how to design peptides with systemic efficacy. To address this problem, we des...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lakshmaiah Narayana, Jayaram, Mishra, Biswajit, Lushnikova, Tamara, Wu, Qianhui, Chhonker, Yashpal S., Zhang, Yingxia, Zarena, D., Salnikov, Evgeniy S., Dang, Xiangli, Wang, Fangyu, Murphy, Caitlin, Foster, Kirk W., Gorantla, Santhi, Bechinger, Burkhard, Murry, Daryl J., Wang, Guangshun
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431008/
https://ncbi.nlm.nih.gov/pubmed/32723829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005540117
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