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Amino Acid Composition Determines Peptide Activity Spectrum and Hot-Spot-Based Design of Merecidin
There is a great interest in developing the only human cathelicidin into therapeutic molecules. The major antimicrobial region of human LL-37 corresponds to residues 17–32. The resultant peptide GF-17 shows a broad spectrum of antimicrobial activity against both Gram-positive and negative bacteria....
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| Udgivet i: | Adv Biosyst |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379907/ https://ncbi.nlm.nih.gov/pubmed/30800727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201700259 |
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