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Amino Acid Composition Determines Peptide Activity Spectrum and Hot-Spot-Based Design of Merecidin

There is a great interest in developing the only human cathelicidin into therapeutic molecules. The major antimicrobial region of human LL-37 corresponds to residues 17–32. The resultant peptide GF-17 shows a broad spectrum of antimicrobial activity against both Gram-positive and negative bacteria....

詳細記述

保存先:
書誌詳細
出版年:Adv Biosyst
主要な著者: Wang, Xiuqing, Mishra, Biswajit, Lushnikova, Tamara, Narayana, Jayaram Lakshmaiah, Wang, Guangshun
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379907/
https://ncbi.nlm.nih.gov/pubmed/30800727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201700259
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