Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

Only a single drug against schistosomiasis is currently available and new drug development is urgently required but very few drug targets have been validated and characterised. However, regulatory systems including cyclic nucleotide metabolism are emerging as primary candidates for drug discovery. H...

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Bibliografski detalji
Izdano u:PLoS Negl Trop Dis
Glavni autori: Munday, Jane C., Kunz, Stefan, Kalejaiye, Titilola D., Siderius, Marco, Schroeder, Susanne, Paape, Daniel, Alghamdi, Ali H., Abbasi, Zainab, Huang, Sheng Xiang, Donachie, Anne-Marie, William, Samia, Sabra, Abdel Nasser, Sterk, Geert Jan, Botros, Sanaa S., Brown, David G., Hoffman, Charles S., Leurs, Rob, de Koning, Harry P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430754/
https://ncbi.nlm.nih.gov/pubmed/32730343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008447
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