Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation

Biogenesis of mammalian mitochondrial ribosomes (mitoribosomes) involves several conserved small GTPases. Here, we report that the Obg family protein GTPBP5 or MTG2 is a mitochondrial protein whose absence in a TALEN-induced HEK293T knockout (KO) cell line leads to severely decreased levels of the 5...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Maiti, Priyanka, Antonicka, Hana, Gingras, Anne-Claude, Shoubridge, Eric A, Barrientos, Antoni
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430652/
https://ncbi.nlm.nih.gov/pubmed/32652011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa592
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki