Pathogenic Germline Mutations in DNA Repair Genes in Combination With Cancer Treatment Exposures and Risk of Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer

PURPOSE: To investigate cancer treatment plus pathogenic germline mutations (PGMs) in DNA repair genes (DRGs) for identification of childhood cancer survivors at increased risk of subsequent neoplasms (SNs). METHODS: Whole-genome sequencing was performed on blood-derived DNA from survivors in the St...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Oncol
Prif Awduron: Qin, Na, Wang, Zhaoming, Liu, Qi, Song, Nan, Wilson, Carmen L., Ehrhardt, Matthew J., Shelton, Kyla, Easton, John, Mulder, Heather, Kennetz, Dennis, Edmonson, Michael N., Rusch, Michael C., Downing, James R., Hudson, Melissa M., Nichols, Kim E., Zhang, Jinghui, Robison, Leslie L., Yasui, Yutaka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2020
Pynciau:
ORIGINAL REPORTS
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430217/
https://ncbi.nlm.nih.gov/pubmed/32496904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.02760
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