The kappa opioid receptor agonist U50,488H did not affect brain-stimulation reward while it elicited conditioned place aversion in mice

OBJECTIVE: Selective kappa opioid receptor (KOR) agonists were shown to produce a dose-dependent depression of brain-stimulation reward (BSR) in the rat intracranial self-stimulation (ICSS) tests. However, limited studies using mice produced less conclusive results. Here the effects of U50,488H were...

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Publicado en:BMC Res Notes
Main Authors: Huang, Peng, Gentile, Taylor A., Muschamp, John W., Liu-Chen, Lee-Yuan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Note
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429879/
https://ncbi.nlm.nih.gov/pubmed/32799930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05227-7
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