HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53

E6 oncoprotein derived from high-risk human papillomavirus (HPV) drives the development of cervical cancer through p53 degradation. Because cervical cancer therapies to inactivate HPV or E6 protein are not available, alternative strategies are required. Here, we show that HPV-mediated nuclear export...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Yi, Sang Ah, Lee, Dong Hoon, Kim, Go Woon, Ryu, Hyun-Wook, Park, Jong Woo, Lee, Jaecheol, Han, Jihoon, Park, Jee Hun, Oh, Hwamok, Lee, Jieun, Choi, Junjeong, Kim, Hyun-Soo, Kang, Hyeok Gu, Kim, Da-Hyun, Chun, Kyung-Hee, You, Jueng Soo, Han, Jeung-Whan, Kwon, So Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429875/
https://ncbi.nlm.nih.gov/pubmed/32203172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0520-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados