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Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy
Hippo signalling regulates eye growth during embryogenesis through its effectors YAP and TAZ. Taking advantage of a Yap heterozygous mouse line, we here sought to examine its function in adult neural retina, where YAP expression is restricted to Müller glia. We first discovered an unexpected tempora...
Enregistré dans:
| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429854/ https://ncbi.nlm.nih.gov/pubmed/32801350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02860-9 |
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