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Double the trouble: giant proteins with dual kinase activity in the heart

Obscurin and its homolog, striated muscle preferentially expressed gene (SPEG), constitute a unique group of proteins abundantly expressed in striated muscles that contain two tandemly arranged MLCK-like kinases. The physiological significance of the dual kinase motifs is largely understudied; howev...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Main Authors: Grogan, Alyssa, Tsakiroglou, Panagiotis, Kontrogianni-Konstantopoulos, Aikaterini
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429600/
https://ncbi.nlm.nih.gov/pubmed/32638332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-020-00715-3
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