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A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution

C. elegans is an animal with few cells, but a striking diversity of cell types. Here, we characterize the molecular basis for their specification by profiling the transcriptomes of 86,024 single embryonic cells. We identify 502 terminal and pre-terminal cell types, mapping most single cell transcrip...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Packer, Jonathan S., Zhu, Qin, Huynh, Chau, Sivaramakrishnan, Priya, Preston, Elicia, Dueck, Hannah, Stefanik, Derek, Tan, Kai, Trapnell, Cole, Kim, Junhyong, Waterston, Robert H., Murray, John I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428862/
https://ncbi.nlm.nih.gov/pubmed/31488706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax1971
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