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The evolution of metapopulation dynamics and the number of stem cells in intestinal crypts and other tissue structures in multicellular bodies

Carcinogenesis is a process of somatic evolution. Previous models of stem and transient amplifying cells in epithelial proliferating units like colonic crypts showed that intermediate numbers of stem cells in a crypt should optimally prevent progression to cancer. If a stem cell population is too sm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Evol Appl
Egile Nagusiak: Birtwell, David, Luebeck, Georg, Maley, Carlo C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428809/
https://ncbi.nlm.nih.gov/pubmed/32821281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.13069
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