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Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs

OBJECTIVES: Occupational exposure to trichloroethylene (TCE) induces trichloroethylene hypersensitivity syndrome (TCEHS), which causes hypersensitivity dermatitis and hepatitis. However, whether TCE itself or its two metabolites, trichloroethanol (TCEOH) and trichloroacetic acid (TCA), are involved...

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Detalhes bibliográficos
Publicado no:J Occup Health
Main Authors: Zhao, Na, Song, Xiangrong, Naito, Hisao, Li, Hongling, Huang, Yongshun, Liu, Lili, Lu, Fengrong, Cai, Tingfeng, Ito, Yuki, Kamijima, Michihiro, Huang, Hanlin, Nakajima, Tamie, Wang, Hailan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428806/
https://ncbi.nlm.nih.gov/pubmed/32799435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1348-9585.12142
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