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Haspin kinase modulates nuclear architecture and Polycomb-dependent gene silencing

Haspin, a highly conserved kinase in eukaryotes, has been shown to be responsible for phosphorylation of histone H3 at threonine 3 (H3T3ph) during mitosis, in mammals and yeast. Here we report that haspin is the kinase that phosphorylates H3T3 in Drosophila melanogaster and it is involved in sister...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Fresán, Ujué, Rodríguez-Sánchez, Maria A., Reina, Oscar, Corces, Victor G., Espinàs, M. Lluisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428214/
https://ncbi.nlm.nih.gov/pubmed/32750047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008962
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