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Haspin kinase modulates nuclear architecture and Polycomb-dependent gene silencing

Haspin, a highly conserved kinase in eukaryotes, has been shown to be responsible for phosphorylation of histone H3 at threonine 3 (H3T3ph) during mitosis, in mammals and yeast. Here we report that haspin is the kinase that phosphorylates H3T3 in Drosophila melanogaster and it is involved in sister...

詳細記述

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書誌詳細
出版年:PLoS Genet
主要な著者: Fresán, Ujué, Rodríguez-Sánchez, Maria A., Reina, Oscar, Corces, Victor G., Espinàs, M. Lluisa
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428214/
https://ncbi.nlm.nih.gov/pubmed/32750047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008962
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