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Quantifying synergy in the bioassay-guided fractionation of natural product extracts

Mixtures of drugs often have greater therapeutic value than any of their constituent drugs alone, and such combination therapies are widely used to treat diseases such as cancer, malaria, and viral infections. However, developing useful drug mixtures is challenging due to complex interactions betwee...

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Bibliographic Details
Published in:PLoS One
Main Authors: Dettweiler, Micah, Marquez, Lewis, Bao, Max, Quave, Cassandra L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428089/
https://ncbi.nlm.nih.gov/pubmed/32797045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235723
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