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Quantifying synergy in the bioassay-guided fractionation of natural product extracts

Mixtures of drugs often have greater therapeutic value than any of their constituent drugs alone, and such combination therapies are widely used to treat diseases such as cancer, malaria, and viral infections. However, developing useful drug mixtures is challenging due to complex interactions betwee...

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Pubblicato in:PLoS One
Autori principali: Dettweiler, Micah, Marquez, Lewis, Bao, Max, Quave, Cassandra L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428089/
https://ncbi.nlm.nih.gov/pubmed/32797045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235723
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