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Prostaglandin E Receptor EP4 expression, survival and pattern of recurrence in locally advanced NSCLC
BACKGROUND: Elevated COX-2 expression has been correlated with inferior outcome in NSCLC. COX-2 catalyzes the transformation of arachidonate to PGE2. We and others have demonstrated that PGE2 induces proliferation and metastatic spread and immunosuppression through the G protein-coupled EP4 receptor...
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| Pubblicato in: | Lung Cancer |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7428069/ https://ncbi.nlm.nih.gov/pubmed/27794413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2016.09.011 |
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