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Kidney-based in vivo model for drug-induced nephrotoxicity testing

The need is critical and urgent for a real-time, highly specific, and sensitive acute kidney injury biomarker. This study sought to establish a sensitive and specific Miox-NanoLuc transgenic mouse for early detection of drug-induced nephrotoxicity. We generated Miox-NanoLuc transgenic mice with kidn...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chiou, Yuan-Yow, Jiang, Si-Tse, Ding, Yu-Sian, Cheng, Yu-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428004/
https://ncbi.nlm.nih.gov/pubmed/32796873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70502-3
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