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Advances in predictive in vitro models of drug-induced nephrotoxicity
In vitro screens for nephrotoxicity are currently poorly predictive of toxicity in humans. Although the functional proteins that are expressed by nephron tubules and mediate drug susceptibility are well known, current in vitro cellular models poorly replicate both the morphology and the function of...
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| Udgivet i: | Nat Rev Nephrol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013592/ https://ncbi.nlm.nih.gov/pubmed/29626199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41581-018-0003-9 |
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