An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution

Group 3 innate lymphoid cells (ILC3) are an important regulator for immunity, inflammation and tissue homeostasis in the intestine, but how ILC3 activation is regulated remains elusive. Here we identify a new circular RNA (circRNA) circKcnt2 that is induced in ILC3s during intestinal inflammation. D...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Benyu, Ye, Buqing, Zhu, Xiaoxiao, Yang, Liuliu, Li, Huimu, Liu, Nian, Zhu, Pingping, Lu, Tiankun, He, Luyun, Tian, Yong, Fan, Zusen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427797/
https://ncbi.nlm.nih.gov/pubmed/32796851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17944-5
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