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An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase

Acetyl coenzyme A (Ac-CoA)-dependent N-acetylation is performed by arylalkylamine N-acetyltransferase (AANAT) and is important in many biofunctions. AANAT catalyzes N-acetylation through an ordered sequential mechanism in which cofactor (Ac-CoA) binds first, with substrate binding afterward. No tern...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Wu, Chu-Ya, Hu, I-Chen, Yang, Yi-Chen, Ding, Wei-Cheng, Lai, Chih-Hsuan, Lee, Yi-Zong, Liu, Yi-Chung, Cheng, Hui-Chun, Lyu, Ping-Chiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427786/
https://ncbi.nlm.nih.gov/pubmed/32796911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01177-9
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