Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis

Nucleus pulposus-derived stem/progenitor cells (NPSCs) provide novel prospects for the regeneration of degenerated intervertebral disc (IVD). Nevertheless, with aging and degeneration of IVD, the frequency of NPSCs markedly decreases. Excessive cell death could be the main reason for declined freque...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Hu, Binwu, Zhang, Shuo, Liu, Weijian, Wang, Peng, Chen, Songfeng, Lv, Xiao, Shi, Deyao, Ma, Kaige, Wang, Baichuan, Wu, Yongchao, Shao, Zengwu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427414/
https://ncbi.nlm.nih.gov/pubmed/32850811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00685
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