Tauroursodeoxycholic Acid Protects Nucleus Pulposus Cells from Compression-Induced Apoptosis and Necroptosis via Inhibiting Endoplasmic Reticulum Stress

Tauroursodeoxycholic acid (TUDCA) is a kind of hydrophilic bile acid, which could protect cells from death via inhibiting endoplasmic reticulum (ER) stress. However, the role of TUDCA in compression-induced intervertebral disc degeneration (IVDD) has not been elucidated. Here, we used a previously d...

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Publicat a:Evid Based Complement Alternat Med
Autors principals: Wang, Wenzheng, Qing, Xiangcheng, Wang, Baichuan, Ma, Kaige, Wei, Yulong, Shao, Zengwu
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867595/
https://ncbi.nlm.nih.gov/pubmed/29721028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6719460
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