Role of 1-Deoxysphingolipids in docetaxel neurotoxicity

A major dose-limiting side effect of docetaxel chemotherapy is peripheral neuropathy. Patients’ symptoms include pain, numbness, tingling and burning sensations, and motor weakness in the extremities. The molecular mechanism is currently not understood, and there are no treatments available. Previou...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurochem
Päätekijät: Becker, Katrin Anne, Uerschels, Anne-Kathrin, Goins, Laura, Doolen, Suzanne, McQuerry, Kristen Jean, Bielawski, Jacek, Sure, Ulrich, Bieberich, Erhard, Taylor, Bradley K., Gulbins, Erich, Spassieva, Stefka D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426245/
https://ncbi.nlm.nih.gov/pubmed/32058598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14985
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