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Role of 1-Deoxysphingolipids in docetaxel neurotoxicity

A major dose-limiting side effect of docetaxel chemotherapy is peripheral neuropathy. Patients’ symptoms include pain, numbness, tingling and burning sensations, and motor weakness in the extremities. The molecular mechanism is currently not understood, and there are no treatments available. Previou...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Becker, Katrin Anne, Uerschels, Anne-Kathrin, Goins, Laura, Doolen, Suzanne, McQuerry, Kristen Jean, Bielawski, Jacek, Sure, Ulrich, Bieberich, Erhard, Taylor, Bradley K., Gulbins, Erich, Spassieva, Stefka D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426245/
https://ncbi.nlm.nih.gov/pubmed/32058598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14985
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