A human-specific VNTR in the TRIB3 promoter causes gene expression variation between individuals

Tribbles homolog 3 (TRIB3) is pseudokinase involved in intracellular regulatory processes and has been implicated in several diseases. In this article, we report that human TRIB3 promoter contains a 33-bp variable number tandem repeat (VNTR) and characterize the heterogeneity and function of this ge...

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發表在:PLoS Genet
Main Authors: Örd, Tiit, Puurand, Tarmo, Örd, Daima, Annilo, Tarmo, Möls, Märt, Remm, Maido, Örd, Tõnis
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425993/
https://ncbi.nlm.nih.gov/pubmed/32745133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008981
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