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Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step

Human cytomegalovirus (HCMV) is one of the main causative agents of congenital viral infection in neonates. HCMV infection also causes serious morbidity and mortality among organ transplant patients. Glycoprotein B (gB) is a major target for HCMV neutralizing antibodies, yet the underlying neutraliz...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Ye, Xiaohua, Su, Hang, Wrapp, Daniel, Freed, Daniel C., Li, Fengsheng, Yuan, Zihao, Tang, Aimin, Li, Leike, Ku, Zhiqiang, Xiong, Wei, Jaijyan, Dabbu, Zhu, Hua, Wang, Dai, McLellan, Jason S., Zhang, Ningyan, Fu, Tong-Ming, An, Zhiqiang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425986/
https://ncbi.nlm.nih.gov/pubmed/32745149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008736
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