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Sphingosine Kinase-1 is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.

Sphingosine-1-phosphate (S1P) produced by sphingosine kinases (SPHK1 and SPHK2) is a signaling molecule involved in cell proliferation and formation of cellular junctions. In this study, we characterized the retinas of Sphk1 knockout (KO) mice by electron microscopy and immunocytochemistry. We also...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Wilkerson, Joseph L., Stiles, Megan A., Gurley, Jami M., Grambergs, Richard C., Gu, Xiaowu, Elliott, Michael H., Proia, Richard L., Mandal, Nawajes A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425817/
https://ncbi.nlm.nih.gov/pubmed/30997640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-1599-x
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