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Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs
PURPOSE: Cyclic adenosine monophosphate (cAMP) and peroxisome proliferator-activated receptor alpha (PPARα) levels mediate extracellular matrix (ECM) changes by altering the levels of hypoxia-inducible factor 1-alpha (HIF-1α) in various tissues. We aimed to determine, in the sclera of guinea pigs, w...
Gespeichert in:
| Veröffentlicht in: | Invest Ophthalmol Vis Sci |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7425689/ https://ncbi.nlm.nih.gov/pubmed/32725213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.8.44 |
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