2-methylbenzoyl berbamine, a multi-targeted inhibitor, suppresses the growth of human osteosarcoma through disabling NF-κB, ERK and AKT signaling networks

Osteosarcoma is the most common malignant bone tumor in children and young adults, and it has a survival rate of only 60% with current cytotoxic chemotherapy combined with aggressive surgery. The aim of this study was to evaluate the therapeutic efficacy of the berbamine derivative 2-methylbenzoyl b...

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Publicado en:Aging (Albany NY)
Autores principales: Li, Weixu, Li, Yan, Tian, Wenjia, Han, Xiuguo, Zhao, Jie, Xin, Zengfeng, Hu, Hejia, Li, Jun, Hang, Kai, Xu, Rongzhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425514/
https://ncbi.nlm.nih.gov/pubmed/32713851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103565
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