Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma

Glioblastoma is a fatal disease in which most targeted therapies have clinically failed. However, pharmacological reactivation of tumour suppressors has not been thoroughly studied as yet as a glioblastoma therapeutic strategy. Tumour suppressor protein phosphatase 2A is inhibited by non-genetic mec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Commun
Prif Awduron: Merisaari, Joni, Denisova, Oxana V, Doroszko, Milena, Le Joncour, Vadim, Johansson, Patrik, Leenders, William P J, Kastrinsky, David B, Zaware, Nilesh, Narla, Goutham, Laakkonen, Pirjo, Nelander, Sven, Ohlmeyer, Michael, Westermarck, Jukka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425423/
https://ncbi.nlm.nih.gov/pubmed/32954276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa002
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