Putaminal diffusion tensor imaging measures predict disease severity across human prion diseases

Therapeutic trials of disease-modifying agents in neurodegenerative disease typically require several hundred participants and long durations for clinical endpoints. Trials of this size are not feasible for prion diseases, rare dementia disorders associated with misfolding of prion protein. In this...

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Detalhes bibliográficos
Publicado no:Brain Commun
Main Authors: Hyare, Harpreet, De Vita, Enrico, Porter, Marie-Claire, Simpson, Ivor, Ridgway, Gerard, Lowe, Jessica, Thompson, Andrew, Carswell, Chris, Ourselin, Sebastien, Modat, Marc, Dos Santos Canas, Liane, Caine, Diana, Fox, Zoe, Rudge, Peter, Collinge, John, Mead, Simon, Thornton, John S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425333/
https://ncbi.nlm.nih.gov/pubmed/32954290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa032
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