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Novel Strong Cation Exchange Ultra-Performance Liquid Chromatography Coupled to UV and MS Detectors for Robust Characterization of ADC Charge Variants
ADCs (antibody-drug conjugates) are powerful new antibody-based drugs that require advanced analytics for full characterization of the antibody charge variants and the drug payload. We set out to develop novel ion exchange UPLC-UV-MS methods that could be used on a small footprint UPLC-UV-MS platfor...
Zapisane w:
Wydane w: | J Biomol Tech |
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Główni autorzy: | , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Association of Biomolecular Resource Facilities
2020
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7424885/ |
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