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Proximal charge effects on guest binding to a non-polar pocket

Science still does not have the ability to accurately predict the affinity that ligands have for proteins. In an attempt to address this, the Statistical Assessment of Modeling of Proteins and Ligands (SAMPL) series of blind predictive challenges is a community-wide exercise aimed at advancing compu...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Suating, Paolo, Nguyen, Thong T., Ernst, Nicholas E., Wang, Yang, Jordan, Jacobs H., Gibb, Corinne L. D., Ashbaugh, Henry S., Gibb, Bruce C.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424593/
https://ncbi.nlm.nih.gov/pubmed/32864079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06268h
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