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Proximal charge effects on guest binding to a non-polar pocket

Science still does not have the ability to accurately predict the affinity that ligands have for proteins. In an attempt to address this, the Statistical Assessment of Modeling of Proteins and Ligands (SAMPL) series of blind predictive challenges is a community-wide exercise aimed at advancing compu...

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Vydáno v:Chem Sci
Hlavní autoři: Suating, Paolo, Nguyen, Thong T., Ernst, Nicholas E., Wang, Yang, Jordan, Jacobs H., Gibb, Corinne L. D., Ashbaugh, Henry S., Gibb, Bruce C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424593/
https://ncbi.nlm.nih.gov/pubmed/32864079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06268h
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