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Expression and Purification of a Bispecific Antibody against CD16 and Hemagglutinin Neuraminidase (HN) in E. Coli for Cancer Immunotherapy

BACKGROUND: : Immunotherapy of cancer by bispecific antibodies (bsAb) is an attractive approach for retargeting immune effector cells including natural killer (NK) cells to the tumor if the proper expression and purification of the bsAb for such applications could be addressed. Herein, we describe E...

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Veröffentlicht in:Rep Biochem Mol Biol
Hauptverfasser: Bahrololoumi Shapourabadi, Mina, Roohvand, Farzin, Arashkia, Arash, Mohajel, Nasir, Abdoli, Shahriyar, Shahosseini, Zahra, Momburg, Frank, Jarahian, Mostafa, Abolhassani4, Mohsen, Azadmanesh, Kayhan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Varastegan Institute for Medical Sciences 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424422/
https://ncbi.nlm.nih.gov/pubmed/32821751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/rbmb.9.1.50
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