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XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction

Transcriptomic signature of XPO1 was highly expressed and inversely related to left ventricular function in ischemic cardiomyopathy patients. We hypothesized that treatment with AAV9-shXPO1 attenuates left ventricular dysfunction and remodeling in a myocardial infarction rat model. We induced myocar...

詳細記述

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書誌詳細
出版年:J Cardiovasc Transl Res
主要な著者: García-Manzanares, María, Tarazón, Estefanía, Ortega, Ana, Gil-Cayuela, Carolina, Martínez-Dolz, Luis, González-Juanatey, José Ramón, Lago, Francisca, Portolés, Manuel, Roselló-Lletí, Esther, Rivera, Miguel
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423868/
https://ncbi.nlm.nih.gov/pubmed/31768947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-019-09932-y
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