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Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction

AIMS: Disruptions in cardiac ion channels have shown to influence the impaired cardiac contraction in heart failure. We sought to determine the altered gene expression profile of this category in dilated cardiomyopathy (DCM) patients and relate the altered gene expression with the clinical signs pre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ortega, Ana, Tarazón, Estefanía, Roselló-Lletí, Esther, Gil-Cayuela, Carolina, Lago, Francisca, González-Juanatey, Jose-Ramón, Cinca, Juan, Jorge, Esther, Martínez-Dolz, Luis, Portolés, Manuel, Rivera, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692400/
https://ncbi.nlm.nih.gov/pubmed/26710323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145518
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