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Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction

AIMS: Disruptions in cardiac ion channels have shown to influence the impaired cardiac contraction in heart failure. We sought to determine the altered gene expression profile of this category in dilated cardiomyopathy (DCM) patients and relate the altered gene expression with the clinical signs pre...

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Vydáno v:PLoS One
Hlavní autoři: Ortega, Ana, Tarazón, Estefanía, Roselló-Lletí, Esther, Gil-Cayuela, Carolina, Lago, Francisca, González-Juanatey, Jose-Ramón, Cinca, Juan, Jorge, Esther, Martínez-Dolz, Luis, Portolés, Manuel, Rivera, Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692400/
https://ncbi.nlm.nih.gov/pubmed/26710323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145518
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