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Cerebellar Predominant Increase in mRNA Expression Levels of Sirt1 and Sirt3 Isoforms in a Transgenic Mouse Model of Huntington’s Disease
The potential role of Sirt1 and Sirt2 subtypes of Sirtuins (class III NAD(+)-dependent deacetylases) in the pathogenesis of Huntington’s disease (HD) has been extensively studied yielding some controversial results. However, data regarding the involvement of Sirt3 and their variants in HD are consid...
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| Publicado en: | Neurochem Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer US
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7423862/ https://ncbi.nlm.nih.gov/pubmed/32524313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-020-03069-0 |
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