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Gene variants and expression changes of SIRT1 and SIRT6 in peripheral blood are associated with Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disease caused by complex interaction between genetic and environmental factors. There is a growing body of evidence of the involvement of sirtuins (SIRTs) in disease pathomechanism. SIRTs are NAD+-dependent histone deacetylases which take part in vari...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Maszlag-Török, Rita, Boros, Fanni A., Vécsei, László, Klivényi, Péter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140123/
https://ncbi.nlm.nih.gov/pubmed/34021216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90059-z
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