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Synergistic effects of Bcl-2 inhibitors with AZD9291 on overcoming the acquired resistance of AZD9291 in H1975 cells

Non-small cell lung cancer (NSCLC) patients with epithermal growth factor receptor (EGFR) mutations can be treated with EGFR-tyrosine kinase inhibitors (EGFR-TKIs), however, development of acquired resistance could significantly limit curative effects of EGFR-TKIs. Different mechanisms of acquired r...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Arch Toxicol
Päätekijät: Liu, Zhongwei, Gao, Weimin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423640/
https://ncbi.nlm.nih.gov/pubmed/32577785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02816-0
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