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Fluoroalkylation promotes cytosolic peptide delivery

Cytosolic delivery of peptides remains a challenging task owing to their susceptibility to enzymatic degradation and the existence of multiple intracellular barriers. Here, we report a new strategy to address these issues by decoration of a fluorous tag on the terminal of cargo peptides. The fluorou...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Rong, Guangyu, Wang, Changping, Chen, Lijie, Yan, Yang, Cheng, Yiyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423368/
https://ncbi.nlm.nih.gov/pubmed/32851155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1774
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