A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

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Bibliographic Details
Published in:eLife
Main Authors: Gaertner, Bjoern, van Heesch, Sebastiaan, Schneider-Lunitz, Valentin, Schulz, Jana Felicitas, Witte, Franziska, Blachut, Susanne, Nguyen, Steven, Wong, Regina, Matta, Ileana, Hübner, Norbert, Sander, Maike
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Computational and Systems Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423336/
https://ncbi.nlm.nih.gov/pubmed/32744504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58659
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