A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

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發表在:eLife
Main Authors: Gaertner, Bjoern, van Heesch, Sebastiaan, Schneider-Lunitz, Valentin, Schulz, Jana Felicitas, Witte, Franziska, Blachut, Susanne, Nguyen, Steven, Wong, Regina, Matta, Ileana, Hübner, Norbert, Sander, Maike
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2020
主題:
Computational and Systems Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423336/
https://ncbi.nlm.nih.gov/pubmed/32744504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58659
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