A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

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Vydáno v:eLife
Hlavní autoři: Gaertner, Bjoern, van Heesch, Sebastiaan, Schneider-Lunitz, Valentin, Schulz, Jana Felicitas, Witte, Franziska, Blachut, Susanne, Nguyen, Steven, Wong, Regina, Matta, Ileana, Hübner, Norbert, Sander, Maike
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Computational and Systems Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423336/
https://ncbi.nlm.nih.gov/pubmed/32744504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58659
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