A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

Long noncoding RNAs (lncRNAs) are a heterogenous group of RNAs, which can encode small proteins. The extent to which developmentally regulated lncRNAs are translated and whether the produced microproteins are relevant for human development is unknown. Using a human embryonic stem cell (hESC)-based p...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Gaertner, Bjoern, van Heesch, Sebastiaan, Schneider-Lunitz, Valentin, Schulz, Jana Felicitas, Witte, Franziska, Blachut, Susanne, Nguyen, Steven, Wong, Regina, Matta, Ileana, Hübner, Norbert, Sander, Maike
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Computational and Systems Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423336/
https://ncbi.nlm.nih.gov/pubmed/32744504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58659
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