IL-6 regulates CCR5 expression and immunosuppressive capacity of MDSC in murine melanoma

BACKGROUND: Myeloid-derived suppressor cells (MDSC) play a major role in the immunosuppressive melanoma microenvironment. They are generated under chronic inflammatory conditions characterized by the constant production of inflammatory cytokines, chemokines and growth factors, including IL-6. Recrui...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Weber, Rebekka, Riester, Zeno, Hüser, Laura, Sticht, Carsten, Siebenmorgen, Alina, Groth, Christopher, Hu, Xiaoying, Altevogt, Peter, Utikal, Jochen S, Umansky, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422659/
https://ncbi.nlm.nih.gov/pubmed/32788238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000949
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